Refereed Publications
(since 1995)

1. Welshons, W.V. and Judy, B.M., 1995. Nuclear vs. translocating steroid receptor models and the excluded middle. Endocrine 3: 1-4.
   
   
2. Mann, F.A., Nonneman, D.J., Pope, E.R., Boothe, H.W., Welshons, W.V. and Ganjam, V.K., 1995. Androgen receptors in the pelvic diaphragm muscles of dogs with and without perineal hernia. Am. J. Vet. Res. 56: 134-139.
   
   
3. Taylor, J.A., Grady, L.H., Engler, K.S. and Welshons, W.V., 1995. Relationship of growth stimulated by lithium, estradiol and EGF to phospholipase C activity in MCF-7 human breast cancer cells. Breast Cancer Res. Treat. 34: 265-277.
   
   
4. vom Saal, F.S., Nagel, S.C., Palanza, P., Boechler, M., Parmigiani, S. and Welshons, W.V., 1995. Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behavior in male mice. Toxicol. Lett. 77: 343-350.
   
   
5. Welshons, W.V., Engler, K.S., Taylor, J.A., Grady, L.H. and Curran, E.M., 1995. Lithium-stimulated proliferation and alteration of phosphoinositide metabolites in MCF-7 human breast cancer cells. J. Cell. Physiol. 165: 134-144.
   
   
6. Montano, M.M., Welshons, W.V. and vom Saal, F.S., 1995. Free estradiol in serum and brain uptake of estradiol during fetal and neonatal sexual differentiation in female rats. Biol. Reprod. 53: 1198-1207.
   
   
7. Ruh, M.F., Taylor, J.A., Howlett, A.C. and Welshons, W.V., 1997. Failure of cannabinoid compounds to stimulate estrogen receptors. Biochem. Pharmacol. 53: 35-41.
   
   
8. Nagel, S.C., vom Saal, F.S., Thayer, K.A., Dahr, M.G., Boechler, M. and Welshons, W.V., 1997. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vitro bioactivity of the xenobiotic estrogens bisphenol A and 4-octylphenol. Environ. Health Perspect. 105: 70-76.
   
   
9. vom Saal, F.S., Timms, B.G., Montano, M.M., Palanza, P., Thayer, K.A., Nagel, S.C., Dahr, M.D., Ganjam, V.K., Parmigiani, S. and Welshons, W.V., 1997. Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses. Proc. Natl. Acad. Sci. (USA) 94: 2056-2061.
   
   
10. Welshons, W.V., vom Saal, F.S. and Nagel, S.C., 1997. Relative binding affinity serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol - Response (Letter to the Editor). Environ. Health Perspect. 105: 571-572.
    
    
11. Gray, L.E., Kelce, W.R., Wiese, T., et al., and Welshons, W.V., 1997. Endocrine screening methods workshop report - Detection of estrogenic and androgenic hormonal and antihormonal activity for chemicals that act via receptor or steroidogenic enzyme mechanisms. Reproductive Toxicology 11: 719-750.
    
    
12. Judy, B.M. and Welshons, W.V., 1998. Cellular localization of receptors mediating actions of steroid hormones. In: Handbook of Physiology, Section 7: The Endocrine System, Volume I: Cellular Endocrinology, ed. P.M. Conn and H.M. Goodman, American Physiology Society, pp. 437-460.
    
    
13. vom Saal, F.S., Cooke, P.S., Buchanin, D.L., Palanza, P., Thayer, K.A., Nagel, S.C., Parmigiani, S. and Welshons, W.V., 1998. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production and behavior. Toxicol. Industrial Health 14: 239-260.
    
    
14. Nagel, S.C., vom Saal, F.S. and Welshons, W.V., 1998. The effective free fraction of estradiol and xenoestrogens in human serum measured by whole cell uptake assays: physiology of delivery modifies estrogenic activity. Proc. Soc. Exp. Biol. Med. 217: 300-309.
    
    
15. vom Saal, F.S., Welshons, W.V. and Hansen, L.G., 1998. Organochlorine levels and breast cancer. New England J. Med. 338: 988.
    
    
16. Welshons, W.V., vom Saal, F.S. and Nagel, S.C., 1998. The importance of protocol design and data reporting to research on endocrine disruption - Response. Environ. Health Perspect. 106: A315-A317.
    
    
17. Welshons, W.V., Nagel, S.C., Thayer, K.A., Judy, B.M. and vom Saal, F.S., 1999. Low-dose bioactivity of xenoestrogens in animals: Fetal exposure to low doses of methoxychlor and other xenoestrogens increases adult prostate size in mice. Toxicol. Industrial Health 15: 12-25.
    
    
18. Nagel, S.C., vom Saal, F.S. and Welshons, W.V., 1999. Developmental effects of estrogenic chemicals are predicted by an in vitro assay incorporating modification of cell uptake by serum. J. Steroid Biochem. Molec. Biol. 69: 343-357.
    
    
19. Cunha, G.R., Forsberg, J.G., Golden, R., Haney, A., Iguchi, T., Newbold, R., Swan, S. and Welshons, W., 1999. New approaches for estimating risk from exposure to diethylstilbestrol. Environ. Health Perspect. 107 (Suppl 4): 625-630.
    
    
20. Laux, D.E., Curran, E.M., Welshons, W.V., Lubahn, D.B. and Huang, T.H.M., 1999. Hypermethylation of the Wilms' tumor suppressor gene CpG island in human breast carcinomas. Breast Cancer Res. Treat. 56: 35-43.
    
    
21. Welshons, W.V., Nagel, S.C. and vom Saal, F.S., 2000. Protein binding interactions - Approaches to quantifying "free" and "bound" fractions of genistein and other xenobiotic estrogens in serum. J. Med. Food 2 (3 & 4): 119-121.
    
    
22. Lee, A.V., Guler, B.L., Sun, X., Oesterreich, S., Zhang, Q.P., Curran, E.M. and Welshons, W.V., 2000. Oestrogen receptor is a critical component required for insulin-like growth factor (IGF)-mediated signalling and growth in MCF-7 cells. Eur J Cancer 36 (Suppl 4): 109-110.
    
    
23. vom Saal, F.S. and Welshons, W.V., 2000. NIH Panel Confirms That Endocrine Disrupting Chemicals Cause Effects at Very Low Doses. Risk Policy Report 7: 47-50.Thayer, K.A., Ruhlen, R.L., Howdeshell, K.L., Buchanan, D.L., Cooke, P.S., Preziosi, D.E., Welshons, W.V., Haseman, J.K. and vom Saal, F.S., 2001. Altered prostate growth and daily sperm production in male mice exposed prenatally to sub-clinical doses of 17a-ethinyl estradiol. Human Reproduction 16: 988-996.
    
    
24. Gobert, G.N., Hueser, C.N., Curran, E.M., Sun, Q.-Y., Glinskii, S., Welshons, W.V., Eisenstark, A. and Schatten, H., 2001. Immunolocalization of NuMA and phosphorylated proteins during the cell cycle in human breast and prostate cancer cells as analyzed by immunofluorescence and postembedding immunoelectron microscopy. Histochemistry and Cell Biology, in press.
    
    
25. Oesterreich, S., Zhang, P., Guler, R.L., Sun, X.H., Curran, E.M., Welshons, W.V., Osborne, C.K. and Lee, A.V., 2001. Estrogen receptor a is required for IGF-mediated signaling and growth in MCF-7 breast cancer cells. Cancer Res., in press.
    
    
26. Welshons, W.V., Thayer, K.S., Taylor, J., Judy, B. and vom Saal, F.S. Large effects from small exposures: I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity. Environ. Health Perspect. In press, 2003. [ article in pdf ]

Published Abstracts [ top ]
(since 1995)

1. Nagel, S.C., Thayer, K.A., Boechler, M., Dhar, M., Morellini, F., Taylor, J.A., vom Saal, F.S. and Welshons, W.V., 1995. An in vitro assay to predict the in vivo activity of environmental estrogens. Program of the 28th Annual Meeting of the Society for the Study of Reproduction, Biol. Reprod. 52 (Suppl 1): 96, abstr. 159.
   
   
2. Welshons, W.V., Nagel, S.C., Thayer, K.A., Dhar, M., Taylor, J.A., and vom Saal, F.S., 1995. Enhanced estrogenic activity of phytoestrogens and other estrogen xenobiotics in human serum. Program of the Third International Conference on Phytoestrogens, Little Rock, AR.
   
   
3. Nagel, S.C., Thayer, K.A., Dhar, M., Taylor, J.A., vom Saal, F.S. and Welshons, W.V., 1995. The relative binding affinity-serum modified access (RBA-SMA) assay predicts the bioactivity of xenobiotic estrogens. Program of the Third International Conference on Phytoestrogens, Little Rock, AR.
   
   
4. Ruh, M., Taylor, J., Howlett, A. and Welshons, W., 1996. Estrogen receptors fail to respond to cannabinoid agonists. Program of the 10th International Congress of Endocrinology, p. 573, abstr. P2-676.
   
   
5. Judy, B.M., Greene, G.L. and Welshons, W.V., 1996. Characterization of non-nuclear estrogen receptors (ERNN) in MCF-7 human breast cancer cells by antibody-binding and sedimentation analysis. Program of the 10th International Congress of Endocrinology, p. 575, abstr. P2-683.
   
   
6. Nagel, S.C., vom Saal, F.S., Sharpe-Timms, K.L. and Welshons, W.V., 1996. Free estradiol in human cord serum measured at less than 0.05% using saturation analysis. Program of the 10th International Congress of Endocrinology, p. 855, abstr. P3-401.
   
   
7. Curran, E.M., Judy, B.M., Golomb, M. and Welshons, W.V., 1996. Regulation of estrogen receptor mRNA by EGF, estradiol and TPA in human breast cancer cells. Program of the 10th International Congress of Endocrinology, p. 570, abstr. P2-663.
   
   
8. Huang, T.H.-M., Curran, E.M., Tran, P., McKensie, J.K., Caldwell, C.W. and Welshons, W.V., 1996. Methylation-sensitive restriction fingerprinting: application to detect abnormal DNA methylation in human breast carcinoma. Proc. 87th Ann. Meeting of the Am. Assoc. for Cancer Res. 37: abstr. nnn.
   
   
9. Nagel, S.C., vom Saal, F.S. and Welshons, W.V., 1997. Free (unbound) fraction of xenoestrogens in human serum. Proc. of the Ann. Meeting of the Society of Toxicology, p. nnn, abstr. nnn.Curran, E.M., Laux, D.E., Denver, D.R., Huang, T.H.-M., Lubahn, D.B. and Welshons, W.V., 1997. Growth factor responsiveness and estrogen receptor gene methylation status in estrogen receptor-negative MCF-7 cell sublines. Proc. 88th Ann. Meeting of the Am. Assoc. for Cancer Res. 38: abstr. A3915.
   
   
10. Laux, D.E., Curran, E.M., Malik, K.T., Welshons, W.V., Lubahn, D.B. and Huang, T.H.-M., 1997. Hypermethylation of the Wilms tumor suppressor gene CpG island in human breast carcinomas. Proc. 88th Ann. Meeting of the Am. Assoc. for Cancer Res. 38: abstr. A1195.
    
    
11. Welshons, W.V., Judy, B.M., Nagel, S.C., Taylor, J.A. and vom Saal, F.S., 1997. Estrogen receptor occupancy and response to estradiol and xenoestrogens in MCF-7 cells. Program of the Conference on Estrogens in the Environment IV.
    
    
12. Nagel, S.C., vom Saal, F.S., Sharpe-Timms, K. and Welshons, W.V., 1997. Mechanisms of fetal vulnerability to xenoestrogens. Program of the Conference on Estrogens in the Environment IV.
    
    
13. Howdeshell, K.L., vom Saal, F.S., Thayer, K.A, Benson, S., Baerwald, C. and Welshons, W.V., 1997. Prenatal exposure to an environmentally relevant dose of bisphenol A accelerates puberty in female mice. Program of the Conference on Estrogens in the Environment IV.
    
    
14. Thayer, K.A, Howdeshell, K.L., vom Saal, F.S., Lubahn, D.B., Buchanan, D., Cooke, P. and Welshons, W.V., 1998. Low dose effects of prenatal exposure to estrogens. Program of the first Gordon Research Conference on Endocrine Disruptors, abstr. 21.
    
    
15. deGraffenried, L.A., Welshons, W.V., Curran, E.M. and Fuqua, S.A., 1999. Transcriptional regulation of the estrogen receptor gene minimal promoter in human cancer cells. Program of the 81st Annual Meeting of the Endocrine Society, p. 194, abstr. P1-280.
    
    
16. Ganjam, V.K., Slight, S.H., Hong, G. and Welshons, W.V., 1999. Inhibition of 11ß-hydroxysteroid dehydrogenase (11ß-HSD) in MCF-7 human breast cancer cells as a sensitive marker for estrogenic endocrine disrupters. Program of the 81st Annual Meeting of the Endocrine Society, p. 336, abstr. P2-266.
    
    
17. Lee, A.V., Guler, R.L., Oesterreich, S., deGraffenried, L.A., Fuqua, S.A., Curran, E.M. and Welshons, W.V., 1999. Loss of estrogen receptor in MCF-7 breast cancer cells is associated with reduced IGFR1 and IRS-1 expression, diminished IGF signaling, and a failure to respond mitogenically to IGFs. Program of the 81st Annual Meeting of the Endocrine Society, p. 478, abstr. P3-190.
    
    
18. Ruhlen, R.L., Thayer, K.A., Preziosi, D.E., Howdeshell, K.L., vom Saal, F.S. and Welshons, W.V., 1999. Prenatal ethinyl estradiol exposure increases adult prostate size and prostatic androgen receptors in adult male mice. Program of the 81st Annual Meeting of the Endocrine Society, p. 493, abstr. P3-258.
    
    
19. Lee, A.V., Guler, B.L., Curran, E. and Welshons, W., 1999. Loss of estrogen receptor (ER) in MCF-7 breast cancer cells results in reduced insulin-like growth factor receptor (IGFR1) and insulin receptor substrate (IRS)-1 expression, diminished IGF signaling, and a failure to respond mitogenically to IGFs. Program of International IGF Meeting, p. nnn, abstr. nnn.
    
    
20. Taylor, J.A., Judy, B.M., Rottinghaus, B.A., Blackwell, K.J., Rottinghaus, G.E., Alworth, L.C., vom Saal, F.S. and Welshons, W.V., 1999. Bisphenol A bioaccumulates in the serum of pregnant mice. Program of the Symposium on Environmental Hormones: Past, Present, Future, p. 18-19.
    
    
21. Howdeshell, K.L., Peterman, P.H., Ruhlen, R.L., Judy, B.M., Welshons W.V. and vom Saal, F.S., 1999. Bisphenol A is released from used polycarbonate rodent cages. Program of the Symposium on Environmental Hormones: Past, Present, Future, p. 9.
    
    
22. Ruhlen, R.L., Thayer K.A., Preziosi, D.E., Howdeshell, K.L., Welshons, W.V., vom Saal, F.S., 1999. Fetal exposure to very low doses of ethinyl estradiol increases prostate size and androgen receptors in CF-1 and CD-1 mice. Program of the Symposium on Environmental Hormones: Past, Present, Future, p. 14.
    
    
23. Bolden-Tiller, O.U., Welshons, W.V., Lucy, M.C. and Smith, M.F., 2000. Progesterone receptor mRNA and protein expression in bovine corpora lutea. Program of the 33rd Annual Meeting of the Society for the Study of Reproduction, Biol. Reprod. 62 (Suppl 1): 268, abstr. 411.
    
    
24. Yuan, X., Curran, E.M., Judy, B.M., Welshons, W.V. and Lubahn, D.B., 2000. Comparison of in vitro ligand-binding and transactivation properties of human ERa and ERß. Program of the 82nd Annual Meeting of the Endocrine Society, p. 351, abstr. 1456.
    
    
25. Welshons, W.V., Taylor, J.A., Judy, B.M. and vom Saal, F.S., 2000. Why bisphenol A is weak in the adult yet strong in the fetus. Program of the Meeting on Bisphenol A: Low Dose Effects-High Dose Effects, p. 21.
    
    
26. vom Saal, F.S., Howdeshell, K.L., Ruhlen, R.L., Taylor, J.A., Timms, B.G. and Welshons, W.V.., 2000. High sensitivity of the fetal prostate to endogenous and environmental estrogens. Program of the Meeting on Bisphenol A: Low Dose Effects-High Dose Effects, p. 20.
    
    
27. vom Saal, F.S., Howdeshell, K.L., Ruhlen, R.L., Welshons, W.V., 2001. Fetal levels of endogenous estradiol and exposure to environmental estrogens influence age-related changes in the male and female reproductive system. Program of the India Meeting on Hormones, Development and Behavior.
    
    
28. Welshons, W.V., 2001. Large effects from small exposures: Implications for adult behaviors following fetal exposure to low doses of the environmental estrogen bisphenol A (BPA). Program of the Erice Meeting on Environmental Endocrine Disruptors and Behavior.
    
    
29. Welshons, W.V., Nagel, S.C., Judy, B.M., Taylor, J.A., Howdeshell, K.L., Ruhlen, R.L. and vom Saal, F.S., 2001. In vitro assessment of endocrine disruptors: Activity of the environmental estrogen bisphenol A at levels of current human exposure. Program of the 2001 Congress on In Vitro Biology, p. nnn, abstr. nnn.
    
    
30. Ganjam, V.K., Alworth, L.C., Howdeshell, K.L., Ruhlen, R.L., Slight, S.H., vom Saal, F.S. and Welshons, W.V., 2001. Fetal programming of 11ß-hydroxysteroid dehydrogenase by maternal exposure to estrogen. Program of the 83rd Annual Meeting of the Endocrine Society, p. nnn, abstr. nnn.
    
    
31. Phillips, B.J., Ansell, P.J., Newton, L.G., Taylor, J.A., Ganjam, V.K., Rottinghaus, G.E., Welshons, W.V. and Lubahn, D.B., 2001. 4-Hydroxylated catechol estrogen binding in ERaWT, ERaKO and ArKO mice: Evidence for "ERg"?. Program of the 83rd Annual Meeting of the Endocrine Society, p. nnn, abstr. nnn.
    
    
32. Yuan, X., Curran, E.M., Ansell, P.J., Welshons, W.V. and Lubahn, D.B., 2001. Both in vivo ligand-binding and transcriptional activities of human ERa and ERb are cell-type specific. Program of the 83rd Annual Meeting of the Endocrine Society, p. nnn, abstr. nnn.
    
    
33. Dougherty, M.K., Schumaker, L., Jordan, V.C., Curran, E., Welshons, W.V., El-Ashry, D. and Ellis, M.J., 2001. Estrogen-regulated proliferation influences paclitaxel sensitivity in breast cancer. Proc. 92nd Ann. Meeting of the Am. Assoc. for Cancer Res. Abstract 1947.
    
    
34. Ganjam, V.K., Taylor, J.A., Judy, B.M., Laughlin, M.H., and Welshons, W.V., 2001. Biologically active estrogen in the boar. Program of the 2001 APS Conference on Genome and Hormones: An Integrative Approach to Gender Differences in Physiology, p. nnn, abstr. nnn.

Chapters [ top ]

1. Shull, J.D., Welshons, W.V., Lieberman, M.E. and Gorski, J., 1985. The rat pituitary estrogen receptor: role of the nuclear receptor in the regulation of transcription of the prolactin gene and the nuclear localization of the unoccupied receptor. In: Molecular Mechanism of Steroid Hormone Action, ed. V. Moudgil, Walter De Gruyter Publishing, Berlin, pp. 539-562.
   
   
2. Jordan, V.C., Fritz, N.F., Gottardis, M.M., Mirecki, D.M., Ravdin, P.M., and Welshons, W.V., 1986. Laboratory and clinical research on the hormone dependence of breast cancer: current studies and future prospects. In: Estrogens and Antiestrogens: Basic and Clinical Aspects, ed. V.C. Jordan, University of Wisconsin Press, pp. 501-522.
   
   
3. Lieberman, M.E., Welshons, W.V. and Gorski, J., 1986. Nuclear localization of unoccupied estrogen receptors. In: Estrogens and Antiestrogens: Basic and Clinical Aspects, ed. V.C. Jordan, University of Wisconsin Press, pp. 43-54.
   
   
4. Gorski, J., Welshons, W.V., Sakai, D., Hansen, J., Walent, J., Kassis, J., Shull, J., Stack, G., and Campen, C., 1986. Evolution of a model of estrogen action. Recent Progr. Horm. Res. 42: 297-329.
   
   
5. Welshons, W.V. and Gorski, J., 1986. Nuclear location of estrogen receptors. In: The Receptors vol IV, ed. P.M. Conn, Academic Press, Orlando, pp. 97-147.
   
   
6. Welshons, W.V. and Jordan, V.C., 1987. Heterogeneity of nuclear steroid hormone binding sites with an emphasis on unfilled receptor sites. In: Steroid Hormone Receptors: Their Intracellular Localisation, ed. C.R. Clark, Ellis Horwood and VCH Publishers, pp. 128-154.
   
   
7. Welshons, W.V., Cormier, E.M., Jordan, V.C. and Gorski, J., 1987. Biochemical evidence for the exclusive nuclear localization of the estrogen receptor. In: Gene Regulation by Steroid Hormones vol. III, ed. A.K. Roy and J.H. Clark, Springer-Verlag, New York, pp. 1-20.
   
   
8. Hansen, J.C., Welshons, W.V. and Gorski, J., 1988. Toward a more unified model of steroid hormone receptor structure and function. In: Steroid Receptors and Disease: Cancer, Autoimmune, Bone, and Circulatory Disorders, ed. P.J. Sheridan, K. Blum and M.C. Trachtenberg, Marcel Dekker, New York, pp. 3-21.
   
   
9. Gorski, J., Hansen, J.C. and Welshons, W.V., 1988. Estrogen receptors as nuclear proteins. In: Proc. Symp. Cell Biology of the Uterus, ed. W.W. Leavitt, Plenum Publishing, New York, pp. 13-29.
   
   
10. Jordan, V.C., Robinson, S.P. and Welshons, W.V., 1988. Resistance to antiestrogen therapy. In: Drug Resistance, ed. D. Kessel, CRC Press, Boca Raton, Florida.
    
    
11. Judy, B.M. and Welshons, W.V., 1998. Cellular localization of receptors mediating actions of steroid hormones. In: Handbook of Physiology, Section 7: The Endocrine System, Volume I: Cellular Endocrinology, ed. P.M. Conn and H.M. Goodman, American Physiology Society, pp. 437-460.

Proceedings [ top ]

1. Welshons, W.V., 1998. Persistent organic pollutants (POPs) and endocrine disruption. In: Proceedings of the Subregional Awareness Raising Workshop on Persistent Organic Pollutants (POPs), Cartegena, Colombia, pp. 129-134.
   
   
2. Welshons, W.V., Nagel, S.C., Thayer, K.A., Judy, B.M. and vom Saal, F.S., 1998. Bisphenol A: an oestrogenic hazard from food can linings and dental sealants? In: IBC Conference Proceedings, 3rd IBC UK Conference on Endocrine Disrupters.

Invited Presentations [ top ]
(since 1995)

1. Seminar, Department of Human Biological Chemistry and Genetics, The University of Texas Medical Branch, Galveston, TX: "Non-nuclear estrogen receptors in MCF-7 human breast cancer cells: A subpopulation of receptors positioned for nongenomic steroid actions", September 21, 1995.
   
   
2. Invited Speaker, Third International Conference on Phytoestrogens, Little Rock, AR: "Enhanced estrogenic activity of phytoestrogens and other estrogen xenobiotics in human serum", December 5, 1995.
   
   
3. Seminar, Department of Veterinary Biomedical Sciences, University of Missouri-Columbia, Columbia, MO: "Enhanced activity of environmental estrogens in human serum", February 8, 1996.
   
   
4. Invited Participant, Toxicology Study Selection and Review Committee on Effects of Endocrine Disrupting Chemicals on Fertility and Reproductive Tract Cancers, National Center for Toxicological Research, Jefferson, AR, May 21, 1996.
   
   
5. Invited Participant, Endocrine Screening Testing Methodology Workshop, Nicholas School of the Environment, Duke University, Durham, NC, July 15-16, 1996.
   
   
6. Invited Speaker, Invited Participant, Health Effects of Contemporary-Use Pesticides: The Wildlife/Human Connection (Third Pesticide Wingspread Work Session), Wingspread Conference Center, Racine, WI: "Sensitivity of the fetal rodent prostate to xenoestrogens, and development of assays in vitro to predict estrogenic activity in animals", September 27-29, 1996.
   
   
7. Invited Speaker, Chemical Manufacturers Association, Arlington, VA: "Prediction in vitro of the bioactivity of potential xenoestrogens in animals and humans", October 10, 1996.
   
   
8. Invited Speaker, International Society of Regulatory Toxicology and Pharmacology conference on Assessing the Risks of Adverse Endocrine-Mediated Effects, Research Triangle Park, NC: "Dose-response issues", January 13, 1997.
   
   
9. Invited Participant, Endocrine Disruptor Workshop, Smithsonian Institution, Washington, DC, January 23-24, 1997. (Smithsonian Institution, UN Environ. Program, White House OSTP, and US EPA)
   
   
10. Invited Speaker, Umwelt-Akademie Conference on Infertility - To What Extent Do Pollutants Threaten Our Future?, Stuttgart, Germany: "Developmental effects of low-dose xenoestrogens and assays in vitro to predict them", March 18, 1997.
    
    
11. Invited Speaker, IBC Second International Environmental Congress on Endocrine Disruptors, Washington, DC: "Developmental effects of low-dose estrogens, and in vitro assay systems to predict them", May 6, 1997.
    
    
12. Chairman and Opening Speaker, IBC UK Second International Conference on Hormone Mimicking and Disrupting Substances in the Environment: Endocrine Disrupters in the Environment, London, UK: "Human Reproductive Health, Endocrine Disrupting Effects and the Significance of Hormone Disrupting Substances: An Overview", May 20, 1997.
    
    
13. Seminar, Dalton Cardiovascular Research Center, University of Missouri-Columbia, Columbia, MO: "Significance of estrogenic endocrine disruptors in animals and humans", July 14, 1997.
    
    
14. Invited Speaker, Symposium on Phytoestrogen Research Methods: Chemistry, Analysis and Biological Properties, Tucson, AZ: "Protein binding interactions - Approaches to quantifying "free" and "bound" fractions of genistein and other xenobiotic estrogens in serum", September 22, 1997.
    
    
15. Invited Speaker, NIH Endocrine Disruptor Conference, The Community Health Project, Bethesda, MD: "Environmental estrogen action", October 23, 1997.
    
    
16. Reproductive Physiology Seminar, Dept. Animal Sciences, University of Missouri-Columbia, Columbia, MO: "Estrogen action and fetal serum", November 19, 1997.
    
    
17. Invited Speaker and Commonweal representative, United Nations Environment Programme Subregional Workshop on Persistent Organic Pollutants (POPs), Bangkok, Thailand: "Endocrine Disruption at Environmentally Relevant Exposures", November 26, 1997.
    
    
18. Invited Speaker and Commonweal representative, United Nations Environment Programme Subregional Workshop on Persistent Organic Pollutants (POPs), Cartagena, Colombia: "POPs and Endocrine Disruption", January 27, 1998.
    
    
19. Invited Speaker, IBC Third International Environmental Congress on Endocrine Disruptors, Washington, DC: "Low dose issues in endocrine disruption", April 14, 1998.
    
    
20. Invited Participant, NIEHS Workshop on Characterizing the Effects of Endocrine Disruptors on Human Health at Environmental Exposure Levels, Raleigh, NC, May 11-13, 1998.
    
    
21. Invited Speaker, IBC UK Third International Conference on Endocine Disrupters in the Environment, London, UK: "Bisphenol A: An oestrogenic hazard from food can linings and dental sealants?", May 14, 1998.
    
    
22. Invited Speaker, Gordon Research Conference on Endocrine Disruptors, Plymouth State College, Plymouth, NH: "Natural and xenoestrogen action - How the fetus is reached", July 15, 1998.
    
    
23. Invited Speaker, Gordon Research Conference on DNA Alterations in Transformed Cells, Colby-Sawyer College, NH: "Fetal exposure to estrogenic endocrine disruptors and risk factors for hormone-dependent cancers", August 13, 1998.
    
    
24. Panelist, Workshop on Funding for Research in Basic and Applied Biological Sciences, University of Missouri-Columbia, Columbia, MO, October 29, 1998.
    
    
25. Seminar, Department of Veterinary Biomedical Sciences, University of Missouri-Columbia, Columbia, MO: "Endocrine disruption by bisphenol A", November 12, 1998.
    
    
26. Session Chairman (Endocrine Disruption in Humans) and Invited Speaker, The 4th International IBC Conference on Endocrine Disrupters in the Environment, London, UK: "Endocrine disrupting substances in plastics and the risk to human health at low doses", May 12, 1999.
    
    
27. Invited Speaker, Seminars in Environmental Toxicology: Toxicology of Plastic Materials, Institute of Pharmacology, Zurich University, Zurich, Switzerland: "Endocrine disruption by bisphenol A in the developing organism", May 20, 1999.
    
    
28. Invited Speaker, Office on Women's Health Workshop on Silicone Implants and Children's Health, "Bisphenol A (BPA) and estrogenic endocrine disruption - fetal exposure via the mother, at levels of current human exposures, leads to permanent effects on rodent offspring", Washington, DC, Feb 8, 2000.
    
    
29. Main Speaker, 9th Workshop of the Training Program in Environmental Health, Center in Urban Environmental Health, Johns Hopkins University, Baltimore, MD, "Biological Activity of Bisphenol A in Mice at Levels of Current Human Exposure", March 8, 2000.
    
    
30. Seminar, Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL: "Low dose effects of bisphenol A: Why this environmental estrogen is weak in the adult yet strong in the fetus", Sept 29, 2000.
    
    
31. Invited Speaker, Endocrine Disruptors Low Dose Peer Review, NIEHS, Research Triangle Park, NC, "Physiological Dose Range", Oct 10, 2000.
    
    
32. Seminar, Department of Veterinary Biomedical Sciences, University of Missouri-Columbia, Columbia, MO: "Why the environmental estrogen bisphenol A is weak in the adult yet strong in the fetus", Nov 2, 2000.
    
    
33. Invited Speaker, Bisphenol A: Low Dose Effects - High Dose Effects, Max-Planck-Gesellschaft, Berlin, Germany: "Low dose effects of environmental estrogens: Why bisphenol A is weak in the adult yet strong in the fetus", Nov 19, 2000.
    
    
34. Invited Speaker, Symposium on Chemicals in the Environmental: Hazards for Human Development, University of California, Irvine, CA: "Fetal effects of the environmental estrogen bisphenol A in mice at levels of current human exposure", Dec 2, 2000.
    
    
35. Invited Speaker, 2001 Congress on In Vitro Biology, St. Louis, MO: "In vitro assessment of endocrine disruptors: Activity of the environmental estrogen bisphenol A at levels of current human exposure", June 18, 2001.
    

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