F. vom Saal’s Publications

2019

vom Saal, F.S. Flaws in design, execution and interpretation limit CLARITY-BPA’s value for risk assessments of bisphenol A. Basic Clin. Pharmacol. Toxicol. 1-12, 2019. doi: 10.1111/bcpt.13195

2018

vom Saal, F.S., Parmigiani, S., Palanza, P., Bhandari, R.K. Transgenerational Effects on Fertility of Estrogenic Chemicals in Fish. In: F. Ruggiu, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 51st SessionErice, Sicily, August, 2018, World Scientific Publishers, Singapore, 2019.

vom Saal, F.S. The intrauterine position phenomenon. Encyclopedia of Reproduction, Elsevier, London, 2018.

Ricke, W.A, Timms, B.G.. and vom Saal, F.S. Developmental and adult anatomy of the prostate in humans and rodents. Encyclopedia of Reproduction, Elsevier, London, 2018.

vom Saal, F.S. and Welshons, W.V. Estrogen agonists. Encyclopedia of Reproduction, Elsevier, London, 2018.

Taylor, J.A., Shioda, K., Angle, B.R., Mitsunaga, S., Yawata, S., Nagel, S.C., vom Saal, F.S. and Shioda,T. Prenatal exposure to bisphenol A disrupts naturally occurring bimodal DNA methylation at proximal promoter of fggy, an obesity-relevant gene encoding a carbohydrate kinase, in gonadal white adipose tissues of CD-1 mice. Endocrinology, 2018. doi: 10.1210/en.2017-00711

Taylor, J.A., Meng, A., Nagel, S.C., Sommerfield-Sager, J., Shioda, T., vom Saal, F.S. Reduced body weight at weaning followed by increased post-weaning growth rate interacts with part-per-trillion fetal serum concentrations of bisphenol A (BPA) to impair glucose tolerance in male mice. PLoS ONE 13(12): e0208846, 2018. Doi: 10.1371/journal.pone.0208846.

2017

Heindel, J.J., Palanza, P. Parmigiani, S. and vom Saal, F.S.  Increasing Incidence of Disease in Global Populations Across the Lifespan and Generations: Key Role of Environmental Endocrine Disrupting Chemicals. In: F. Ruggiu, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 50th SessionErice, Sicily, August, 2017, World Scientific Publishers, Singapore, 2018.

Nicholson, T.M., Nguyen, J.,  Leverson, G.E., Taylor, J.A., vom Saal, F,S,, Wood, R.W.  and Ricke, R.W. The endocrine disruptor Bisphenol-A is implicated in urinary voiding dysfunction in male mice. Am. J. Physiol. Renal Physiol.315: F1208–F1216, 2018.

Stahlhut, R.W., Taylor, J.A. Nadal, A. Myers, J.P. Dyer, J.A. and vom Saal, F.S. Experimental BPA Exposure and Glucose-Stimulated Insulin Response in Adult Men and Women. J. Endo. Soc. 2(10):1173-1187,  2018. doi: 10.1210/js.2018-00151

vom Saal, F.S., Palanza, P. and Parmigiani, P. Disruption of development by environmental chemicals and psycho-social stress. In: R. C. Ragaini, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 49th Session,Erice, Sicily, August, 2016, World Scientific Publishers, Singapore, 2017.

Denninghoff, J.S. and vom Saal, F.S. Sources of contaminants in the home: indoor air quality and human health. In: Integrative Environmental Health, Editors: A. Cohen and F.S. vom Saal, Oxford University Press, London, p 67-85, 2017.

Cohen, A. and vom Saal, F.S., Editors. Integrative Environmental Health. Oxford University Press, London, 2017. ISBN-13: 978-0190490911

Vandenberg, L.N., Blumberg B., Antoniou, M., Benbrook,C.M. Carroll, L., Colborn, T., Everett, L.G., Hansen, M., Landrigan, P.J., Lanphear, B.P., Mesnage, R., vom Saal, F.S., Welshons, W.V. and Myers, J.P. Is it time to reassess current safety standards for glyphosate-based herbicides?  Journal of Epidemiology and Community Health (JECH) 71(6). Online DOI:10.1136/jech-2016-208463

2016

Myers, J.P., Antoniou, M., Blumberg, B., Carroll, L., Colborn, T., Everett, L.G., Hansen, M., Landrigan, P.J., Lanphear, B.P., Mesnage, R., Vandenberg, L.N., vom Saal, F.S., Welshons, W.V. and Benbrook,C.M. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environmental Health 15:19, 2016. DOI: 10.1186/s12940-016-0117-0

vom Saal, F.S. Endocrine disrupting chemicals threaten fetal health. In: Thomas Berry in Italy: Reflections on Spirituality and Sustainability. Edited by Ferrero, Pacem in Terris Press, 99-114, 2016.

vom Saal, F.S. and Welshons, W.V. Endocrine disruptors: Manmade and Natural Estrogens: Opposite Effects on Assisted Reproduction. Nature Rev 12, 251-252, 2016. DOI: 10.1038/nrendo.2016.38

vom Saal, F.S, Environmental programming of reproduction during fetal life: Effects of intrauterine position and the endocrine disrupting chemical bisphenol A (BPA). J. Anim. Sci. 94:1–15, 2016. DOI: 10.2527/jas2015-0211

Stahlhut RW, van Breemen RB, Gerona RR, Taylor JA, Welshons WV, vom Saal FS. Comment on “optimal exposure biomarkers for nonpersistent chemicals in environmental epidemiology”. Environ Health Perspect 124:A66, 2016.

Trasande, L., Vandenberg, L.N., Bourguignon, J-P., Myers, J.P., Slama, R., vom Saal, F.S., Zoeller, R.T. Peer-reviewed and unbiased research, rather than ‘sound science’, should be used to evaluate endocrine disrupting chemicals. Journal of Epidemiology and Community Health. 70:1051-1056, 2016.

Thaddeus T. Schug, Anne F. Johnson, Linda S. Birnbaum, Theo Colborn, Louis J. Guillette, Jr., David Crews, Terry Collins, Ana M. Soto, Frederick S. vom Saal, John A. McLachlan, Carlos Sonnenschein and Jerrold J. Heindel. Endocrine Disruptors: Past Lessons and Future Directions. Molecular Endocrinology, 30:833-847, 2016.

Heindel, J.J., Blumberg, B., Cave, M., Machtinger, R., Mantovani, A., Mendez, M.A., Nadal, A., Palanza, P., Panzica, G., Sargis, R., Vandenberg, L.N., vom Saal, F.S. Metabolism Disrupting Chemicals and Metabolic Disorders. Reproductive Toxicology, Online October 2016. DOI: 10.1016/j.reprotox.2016.10.001

VandeVoort, C.A., Gerona, R.R., vom Saal, F.S., Tarantal, A.F., Hunt P.A., Hillenweck, A. and Zalko, D. Maternal and fetal pharmacokinetics of oral radio-labeled and authentic bisphenol A in the rhesus monkey. PlosOne 11: e0165410, 2016.

2015

Bhandari, R.K., vom Saal, F.S. and Tillitt, D.E. Transgenerational effects from early developmental exposures to bisphenol A or 17α-ethinylestradiol in medaka, Oryzias latipes. Scientific Reports, 5: 9303, 2015. DOI 10.1038/srep09303

Kassotis, C.D., Alvarezc, D.A., Taylor, J.A., vom Saal, F.S., Nagel, S.C. and Tillitt, D.E. Characterization of Missouri surface waters near point sources of pollution reveals potential novel atmospheric route of exposure for bisphenol A and wastewater hormonal activity pattern. Science of the Total Environment, 524–525: 384–393, 2015. DOI 10.1016/j.scitotenv.2015.04.013

Jandegian, C.M., Deem, S.L., Bhandari, R.K., Holliday, C.M., Nicks, D., Rosenfeld, C.S., Selcer, K.W., Tillitt, D.E., vom Saal, F.S., Velez-Rivera, V. and Yang, Y. Developmental exposure to bisphenol A (BPA) alters sexual differentiation in painted turtles (Chrysemys picta). General and Comparative Endocrinology 215:77-85, 2015. DOI 10.1016/j.ygcen.2015.04.003

Heindel, J.J., vom Saal, F.S., Blumberg, B., Bovolin, P., Calamandrei, G., Ceresini, G., Cohn, B.A., Fabbri, E., Gioiosa, L., Kassotis, C., Legler, J., La Merrill, M. Rizzi, L., Machtinger, R., Mantovani, A., Mendez, M.A. Montanini, L., Molteni, L., Nagel, S.C., Parmigiani, S., Panzica, G., Paterlini, S., Pomatto, V., Ruzzin, J., Sartor, G., Schug, T.T., Street, M., Suvorov, A., Volpi, R., Zoeller, R.T. and Palanza, P. Parma Consensus Statement on Metabolic Disruptors. Environmental Health 14:54, 2015. DOI 10.1186/s12940-015-0042-7

Oreskes, N., Carlat, D. Mann, M.E., Thacker, P.D., vom Saal, F.S. Viewpoint: Why Disclosure Matters. Environmental Science & Technology 49:7527-7528, 2015. doi:10.1021/acs.est.5b02726

Gioisa, L., Palanza, P., Parmigiani, S. and vom Saal, F.S. Risk evaluation of endocrine disrupting chemicals: Effects of developmental exposure to low doses of bisphenol A (BPA) on behavior and physiology in mice (Mus musculus domesticus). Dose Response 1-8, 2015. DOI: 10.1177/1559325815610760

Palanza, P., Nagel, S.C., Parmigiani, S. and vom Saal, F.S. Prenatal exposure to endocrine disruptors (sex, timing and behavioral endpoints). Current Opinion in Behavioral Sciences. 7:69-75, 2015. DOI: org/10.1016/j.cobeha.2015.11.017

2014

vom Saal, F.S., Vandevoort, C.A., Taylor, J.A., Welshons, W.V., Toutain, P-L., Hunt, P.A. Bisphenol A (BPA) pharmacokinetics with daily oral bolus or continuous exposure via silastic capsules in pregnant rhesus monkeys: Relevance for human exposures. Reproductive Toxicology 45:105–116, 2014.

Vandenberg, L.N., Gerona, R.R., Kannan, K., Taylor, J.A., van Breemen, R.B., Dickenson, C.A., Liao, C., Yuan, Y., Newbold, R.R., Padmanabhan, V., vom Saal, F.S., Woodruff, T.J. A round robin approach to the analysis of bisphenol A (BPA) in human blood samples. Environmental Health 13(1):25, 2014. Doi: 10.1186/1476-069X-13-25

Lathi, RB, Liebert, CA, Brookfield, KF, Swan, SH, Taylor, JA, vom Saal, FS, Fujimoto, VY, Baker, VL. Conjugated bisphenol A (BPA) in maternal serum in relation to miscarriage risk. Fertility and Sterility 102:123–128, 2014.

Vandenberg, L.N., Welshons, W.V., vom Saal, F.S., Toutain, P-L., Myers, J.P. Should oral gavage be abandoned in toxicity testing of endocrine disruptors? Environmental Health 13(1):46, 2014.

vom Saal, F.S. and Welshons, W.V. Evidence that serum and urine BPA can be accurately measured without contamination and that hazards can be identified at low, human-relevant BPA exposures when experiments include appropriate controls. Molecular and Cellular Endocrinology, 398:101-113, 2014. DOI 10.1016/j.mce.2014.09.028

Bhandari, R. Deem, S.L., Holliday, D.K., Jandegian, C.M., Kassotis, C.D., Nagel, S.C., Tillitt, D.E. vom Saal, F.S., and Rosenfeld, C.S. Effects of the environmental estrogenic contaminants bisphenol A and 17a-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species. General and Comparative Endocrinology 398:101–113, 2014. DOI 10.1016/j.ygcen.2014.09.014

Hormann, A.M., vom Saal, F.S., Nagel, S.C., Stahlhut, R.W., Moyer, C.L., Ellersieck, M.R., Welshons, W.V., Toutain, P-L and Julia A. Taylor, J.A. Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A (BPA). PLoS One 9, e110509, 2014. DOI 10.1371/journal.pone.0110509

2013

Schug, T.T, R. Abagyan, B Blumberg, T Collins, D Crews, P DeFur, S Dickerson, T Edwards, A Gore, L.J. Guillette, T Hayes, J Heindel, A Moores, K.P. O’Brien, H.B. Patisaul, T Tal, K Thayer, L Vandenberg, J Warner, C Watson, F.S. vom Saal, R.T. Zoeller and J.P. Myers. Designing endocrine disruption out of the next generation of chemicals. Green Chemistry: J. Royal Soc. Chemistry 15:181-198, 2013.

Vandenberg, L.N., Colborn, C., Hayes,, T.B., Heindel,, J.J., Jacobs, D.R. Jr, Lee, D-H, Myers, J.P., Shioda, T., Soto, A.M., vom Saal,, F.S., Welshons, W.V. and Zoeller,,, R.T. Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology. Reprod, Toxicol. 38:1–15, 2013.

Gioiosa, L., Parmigiani, S., vom Saal, F.S., Palanza, P. Effects of bisphenol A on emotional behavior depend upon the timing of exposure, age and gender in mice. Hormones and Behavior 4:598-605, 2013.

Vandenberg, L.N., Hunt, P.A., Myers, J.P. and vom Saal, F.S. Human exposures to bisphenol A: mismatches between data and assumptions. Rev Environ Health 28(1):37–58, 2013.

Angle, B. M., R. P. Do, D. Ponzi, R. W. Stahlhut, B. E. Drury, S. C. Nagel, W. V. Welshons, C. L. Besch-Williford, P. Palanza, S. Parmigiani, F. S. vom Saal and J. A. Taylor. Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): Evidence for non-monotonic effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation. Reproductive Toxicology 42:256-268, 2013. doi.org/10.1016/j.reprotox.2013.07.017

Vandenberg, L.N., Ehrlich, S., Belcher, S.M., Ben-Jonathan, N., Dolinoy, D.C., Hugo, E.S., Hunt, P.A., Newbold, R.R., Rubin, B.S., Saili, K.S., Soto, A.M., Wang, H-S., vom Saal, F.S. Low Dose Effects of Bisphenol A: An Integrated Review of In Vitro, Laboratory Animal and Epidemiology Studies. Endocrine Disruption 1:E1-E20, 2013. doi.org/10.4161/endo.26490

2012

Taylor, J.A., Richter, C.A, Shioda, T., Coser, K., Suzuki, A., Watanabe, H., Iguchi, T. and vom Saal, F.S. Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells. Plos One, 7(10):e48311, 2012.

Schug, T.T., Erlebacher, A., Leibowitz, S., Ma, L., Muglia, L.J., Rando, O.J., Rogers, J.M., Romero. R., vom Saal, F.S. and Wise, D.L.  Fetal Programming and Environmental Exposures: Implications for Prenatal Care and Preterm Birth. Annals New York Acad Sci. 1276:37–46, 2012.

Do, R.P., Stahlhut, R.W., Ponzi, D., vom Saal, F.S. and Taylor, J.A. Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses. Reprod. Toxicol. 34(4):614-621, 2012.

vom Saal, F.S., Coe, B.L., Angle, B.R. and Taylor, J.A. Disruption of development by environmental estrogens: Adult obesity and metabolic disease. In: Obesity: Epidemiology, Pathophysiology and Prevention, Vol 2, Editors: Debasis Bagchi and Harry G. Preuss, CRC Press, Boca Raton, FL, pp 73-83, 2012.

Nicholson, T.M., Ricke, E.A., Marker, P., Miano, J.M., Mayer, R., Timms, B.G., vom Saal, F.S., Wood, R., Ricke, W.A. Testosterone and estradiol-17ß induce new glandular prostatic growth, bladder outlet obstruction, and urinary voiding dysfunction in male mice. Endocrinol. 153:5556-5565, 2012.

Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, vom Saal FS. Endocrine-disrupting Chemicals and Public Health Protection: A Statement of Principles from The Endocrine Society. Endocrinol. 153:4097-4110, 2012.

vom Saal, F.S., Taylor, J.A., Palanza, P. and Parmigiani, S. New Approaches to Risk Evaluation for Chemicals of Emerging Concern (CECs). In: R. C. Ragaini, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 44th Session,Erice, Sicily, August, 2011, World Scientific Publishers, Singapore, 566-578, 2012.

Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, vom Saal FS. Endocrine-disrupting Chemicals and Public Health Protection: A Statement of Principles from The Endocrine Society. Endocrinol. 153:4097-4110, 2012.

vom Saal, F.S. and Hunt, P.A. Opinion: FDA’s decision on BPA exposes Catch 22. Scientific American (http://blogs.scientificamerican.com/guest-blog/2012/06/11/opinion-fdas-decision-on-bpa-exposes-catch-22/), June 11, 2012.

Vandenberg, L.N., Colborn, T., Hayes, T.B., Heindel, J.J., Jacobs, D.R., Lee, D-H., Shioda, T., Soto, A.M., vom Saal, F.S., Welshons, W.V., Zoeller, R.T. and Myers, J.P. A paradigm shift in environmental chemical research: Understanding and expecting “low dose” effects and non-monotonic dose responses. Endocr. Rev. Online March, 2012.

vom Saal, F.S., Nagel, S.C., Coe, B.L., Angle, B.M. and Taylor, J.A. The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. Molec. Cell. Endocrinol. 354:74-84, 2012.

Hanna. C.W., Fujimoto, V.Y., Robinson, W.P., Kim, D., Parsons, P.J., vom Saal, F.S., Taylor, J.A., Steuerwald, A.J. and Bloom, M.S. DNA methylation changes in whole blood associated with exposure to environmental contaminants: mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF. Human Reprod. 27:1401-1410, 2012.

Taylor, J.A., vom Saal, F.S., Welshons, W.V. Drury, B., Rottinghaus, G., Hunt, P.A., Toutain, P-L. and Laffont, C.M. Bisphenol A in thermal paper receipts. Environ. Health Perspect. 120:A15, 2012.

Schug, T.T., Vogel, S.A., Vandenberg, L.N., Braun, J., Hauser, R., Taylor, J.A., vom Saal, F.S., and Heindel, J.J. Bisphenol A. In: Dioxins and Health: Including Other Persistent Organic Pollutants and Endocrine Disruptors. 3rd Edition. Edited by: A. Schecter, Wiley & Sons, New York, pp 381-413, 2012.12.

vom Saal, F.S., Prins, G.S. and Welshons, W.V. Report of very low real world exposure to bisphenol A is unwarranted based on a lack of data and flawed assumptions. Toxicol. Sci. 125:318-320, 2012.

vom Saal, F.S., Coe, B.L., Angle, B.R. and Taylor, J.A. Disruption of development by environmental estrogens: Adult obesity and metabolic disease. In: Obesity: Epidemiology, Pathophysiology and Prevention, Vol 2, Editors: Debasis Bagchi and Harry G. Preuss, CRC Press, Boca Raton, FL, pp 73-83, 2012.

Lankford, D.M. and vom Saal, F.S. Development of a writing intensive capstone course to facilitate the integration and communication of complex issues in biology. J. College Science Teaching 41(4):18-26, 2012.

vom Saal, F.S. Adverse Health Effects of Bisphenol A (BPA): Implications for the use of BPA in hemodialyzers and other medical equipment. Online: http://www.spektrum-der-dialyse.de/themenbereiche/dialyse. Spektrum der Dialyse & Apherese. 2011.

2011

Taylor, J.A., Richter, C.A., Ruhlen, R.L. and vom Saal, F.S. Estrogenic chemicals and drugs: Mechanisms for effects on the developing male urogenital system. J. Steroid Biochem. Mol. Biol. 127:83– 95, 2011.

Bloom, M. S., F. S. vom Saal, D. Kim, J. A. Taylor, J. D. Lamb and V. Y. Fujimoto. Serum unconjugated bisphenol A concentrations in men may influence embryo quality indicators during in vitro fertilization.Environ Toxicol Pharmacol 32:319-23, 2011.

Bloom, M.S., Kim, D., vom Saal, F.S., Taylor, J.A., Cheng, G., Lamb, J.D., and Fujimoto, V.Y. Bisphenol A exposure reduces the estradiol response to gonadotropin stimulation during in vitro fertilization. Fertil. Steril. 96:672-677 e2, 2011.

Sieli, P.T., Jašarevi?, E., Warzak, D.A., Mao, J., Ellersieck, M.R., Liao, C., Kannan, K., Collet, S., Toutain, P.L., vom Saal, F.S. and Rosenfeld, C.S. Comparison of serum bisphenol A concentrations in mice exposed to bisphenol A through the diet versus oral bolus exposure. Environ. Health Perspect. 119:1260-1265, 2011.

Novak, P.J.; Arnold, W.A.; Blazer, V.S.; Halden, R.U.; Klaper, R.D.; Kolpin, D.W.; Kriebel, D.; Love, N.G.; Martinovic, D.; Patisaul, H.B.; Snyder, S.A.; vom Saal, F.S.; Weisbrod, A.V.; Swackhamer, D.L. On the Need for a National (US) Research Program to Elucidate the Potential Risks to Human Health and the Environment Posed by Contaminants of Emerging Concern. Environ. Sci. Technol. 45:3829–3830, 2011.

Novak, P.J., Blazer, V.S., Halden, R.U., Klaper, R.D., Kolpin, D.W., Kriebel, D., Love, N.G., Martinovi?-Weigelt, D., Patisaul, H.B., Snyder, S.A., vom Saal, F.S., Weisbrod, A.V., Swackhamer, D.L. Assessing contaminant risk on a global scale. Nature 471:578 2011.

Ruhlen, RL, Taylor, JA, Mao, J, Kirkpatrick, J, Welshons, WV and vom Saal, FS. Choice of animal feed can alter fetal steroid levels and mask developmental effects of endocrine disrupting chemicals. J Develop Origins Health Disease 2:36-48, 2011.

Fujimoto, V.Y., Kim, D., vom Saal, F.S., Lamb, J.D., Taylor, J.A., and Bloom, M.S. Serum unconjugated bisphenol A concentrations in women adversely influence oocyte quality during in vitro fertilization. Fertil. Steril. 95:1816-1819, 2011.

Taylor, J.A., vom Saal, F.S., Welshons, W.V., Drury, B., Rottinghaus, G., Hunt, P.A., Toutain, P.L., Laffont, C.M. and VandeVoort, C.A.. Similarity of bisphenol A pharmacokinetics in rhesus monkeys and mice: Relevance for human exposure. Environ. Health Perspect. 119:422-430, 2011.

Ela, W.P., D.L. Sedlak, M. Barlaz, H. Henry, D. Muir, D. Swackhamer, E.J. Weber, R.G. Arnold, L. Ferguson, J. Field, E. Furlong, J.P. Giesy, R. U. Halden, T. Henry, R. Hites, K. Hornbuckle, P. Howard, R.G. Luthy, A. Meyer, A.E. Sáez, F.S. vom Saal, C. Vulpe, and M.R. Wiesner. Identifying the next generation of superfund and hazardous waste site contaminants. Environ. Health Perspect. 119:6-10, doi:10.1289/ehp.1002497, 2011.

2010

vom Saal, F.S., Akingbemi, B., Belcher, S., Crain, D., Crews, D., Guidice, L. et al. Flawed Experimental Design Reveals the Need for Guidelines Requiring Appropriate Positive Controls in Endocrine Disruption Research. Toxicological Sciences 115: 612-613, 2010.

vom Saal, F.S., Akingbemi, B., Belcher, S., Crain, D., Crews, D., Guidice, L. et al. Flawed Experimental Design Reveals the Need for Guidelines Requiring Appropriate Positive Controls in Endocrine Disruption Research. Toxicological Sciences 115: 612-613, 2010.

vom Saal, F.S., Taylor, J.A., Palanza, P. and Parmigiani, S. The high-volume hormonally active chemical bisphenol A: Human exposure, health hazards and need to find alternatives. In: R. C. Ragaini, Editor, Proceedings of Conference: ¬International Seminar on Nuclear War and Planetary Emergencies, 42th Session, Erice, Sicily, August, 2009, World Scientific Publishers, Singapore, pp. 763-772, 2010.

2009

Myers, J.P., Zoeller, T.J. and vom Saal, F.S. A clash of old and new scientific concepts in toxicity, with important implications for public health. Environ. Health Perspect. 117:1652–1655, 2009.

Thompson, R.C., Swan, S.H., Moore, C. and vom Saal, F.S. Our plastic age. Philosophical Transactions of the Royal Society B. 364:1973-1976, 2009.

Thompson, R.C., Moore, C., vom Saal, F.S. and Swan, S.H. Plastics, the environment and human health: Current consensus and future trends. Philosophical Transactions of the Royal Society B. 364: 2153-2166, 2009.

Heindel, J.J. and vom Saal, F.S. Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity. Mol. Cell Endocrinol. 304:90-96, 2009.

Talsness, C.E., Andrade, A.J.M., Kuriyama, S.N., Taylor, J.A. and vom Saal, F.S. Components of plastic: experimental studies in animals and relevance for human health. Philosophical Transactions of the Royal Society B. 364:2079-2096, 2009

Myers, JP, vom Saal, FS, Akingbemi, BT, Arizono, K, Belcher, S, Colborn, T, Chahoud, I, Crain, DA, Farabollini, F, Guillette, LJ, Jr., Hassold, T, Ho, SM, Hunt, PA, Iguchi, T, Jobling, S, Kanno, J, Laufer, H, Marcus, M, McLachlan, JA, Nadal, A, Oehlmann, J, Olea, N, Palanza, P, Parmigiani, S, Rubin, BS, Schoenfelder, G, Sonnenschein, C, Soto, AM, Talsness, CE, Taylor, JA, Vandenberg, LN, Vandenbergh, JG, Vogel, S, Watson, CS, Welshons, WV and Zoeller, RT (2009). Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ. Health Perspect. 117:309-315, 2009.

2008

vom Saal, F.S. and Myers, J.P. Bisphenol A and Risk of Metabolic Disorders. JAMA 300(11):1353-1355, 2008.

Palanza, P.L., Gioiosa, L. Parmigiani, S. and vom Saal, F.S. Effects of developmental exposure to bisphenol A on brain and behavior in mice. Environ. Res. 108(2):150-157. 2008.

vom Saal, F.S., Parmigiani, S., Palanza, P.L., Everett, L.G. and Ragaini, R. The plastic world: sources, amounts, ecological impacts and effects on development, reproduction, brain and behavior in aquatic and terrestrial animals and humans. Environ. Res. 108(2):127-130, 2008.

Myers, J.P. and vom Saal, F.S. Should public health standards for endocrine-disrupting compounds be based upon 16th Century dogma or modern endocrinology? San Francisco Medicine 81(1): 30-31, 2008.

Taylor, J.A., Welsons W.V. and vom Saal, F.S. No effect of route of exposure (oral; subcutaneous injection) on plasma bisphenol A throughout 24 hr after administration in neonatal female mice. Reprod. Toxicol. 25:169-176, 2008.

Coe, B.L., Kirkpatrick, J.R., Taylor, J.A. and vom Saal, F.S. A new “crowded uterine horn” mouse model for examining the relationship between fetal growth and adult obesity. Basic Clin. Pharmacol. Toxicol. 102:162-167, 2008.

Heindel, J.J. and vom Saal, F.S. Meeting Report: Batch-to-Batch Variability in Estrogenic Activity in
Commercial Animal Diets—Importance and Approaches for Laboratory
Animal Research
. Environ. Health Perspect. 116:389-393, 2008.

Ruhlen, R.L., Howdeshell, K.L., Mao, J., Taylor, J.A., Bronson, F.H., Newbold, R.R., Welshons, W.V. and vom Saal, F.S. Low phytoestrogen levels in feed increase fetal serum estradiol resulting in the “fetal estrogenization syndrome” and obesity in CD-1 mice. Environ. Health Perspect. 116:322-328, 2008.

2007

vom Saal, F.S., Akingbemi, B.T., Belcher, S.M., Birnbaum, L.S., Crain, D.A., Farabollini, F., Guillette, L.J., Hauser, R., Heindel J.J., Ho, S-M. et al. Chapel Hill expert pamel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod. Toxicol. 24(2):131-138, 2007.

vom Saal, F.S. Could hormone residues be involved? Human Reprod. 22:1503-1505, 2007.

Richter, C.R., Birnbaum, L.S., Farabollini, F., Newbold, R.R., Rubin, B.S., Talsness, C.E., Vandenbergh, J.G., Walser-Kuntz, D.R. and vom Saal, F.S. In vivo effects of bisphenol A in laboratory rodent studies. Reprod. Toxicol. 24:199-224, 2007.

Richter, C.A., Taylor, J.A., Ruhlen, R.R., Welshons, W.V. and vom Saal, F.S. Estradiol and bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate cells. Environ. Health Perspect. 115:902-908, 2007.

2006

vom Saal, F.S. Bisphenol A Eliminates Brain and Behavior Sex Dimorphisms in Mice. How Low Can You Go? Endocrinol. 147:3679-3680, 2006.

Welshons, W.V., Nagel, S.C. and vom Saal, F.S. Large effects from small exposures: III. Mechanisms mediating responses to the low doses of the plastic monomer bisphenol A. Endocrinol. 147:S56-S69, 2006.

vom Saal, F.S. and Welshons, W.V. Large effects from small exposures: II. The importance of positive controls in low-dose research on bisphenol A. Environmental Research 100:50-76, 2006.

2005

Weltje, L., vom Saal, F.S. and Oehlmann, J. Reproductive stimulation by low doses of xenoestrogens contrasts with the view of hormesis as an adaptive response. Human and Experimental Toxicology 24:1-7, 2005.

vom Saal, F.S. Low-dose bisphenol A: confirmed by an extensive literature. Chemistry and Industry 7:14-15, 2005.

vom Saal, F.S. and Hughes, C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ. Health Perspect. 113:926-933, 2005.

Timms, B.G., K.L. Howdeshell, L. Barton, S. Bradley, C.A. Richter and F.S. vom Saal. Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra. Proc. Natl. Acad. Sci., 102: 7014-7019, 2005.

vom Saal, F.S., Richter, C.A., Ruhlen, R.R., Taylor, J.A., Rottinghaus, G.E. and Welshons, W.V. Commercial animal Feed: Variability in estrogenic activity and effects on body weight in mice. Birth Defects Research (Part A) 73:474-475, 2005.

vom Saal, F.S., Nagel, S.C., Timms, B.G. and Welshons, W.V. Implications for human health of the extensive bisphenol A literature showing adverse effects at low doses: A response to attempts to mislead the public. Toxicology, 212:244-252, 2005.

vom Saal, F.S., Richter, C.A. Ruhlen, R.R., Nagel, S.C., Timms, B.G. and Welshons, W.V. Importance of appropriate controls, animal feed and animal models in interpreting results from low-dose studies of bisphenol A. Birth Defects Research (Part A) 73: 140-145, 2005.

Richter, C.A., Timms, B.G. and vom Saal, F.S. Prostate Development: Mechanisms for opposite effects of low and high doses of estrogenic chemicals. In: R.K. Naz, ed. Endocrine Disruptors (2nd Edition): Effects on Male and Female Reproductive Systems. CRC Press, Boca Raton, FL, 379-410, 2005.

2004

Myers, J.P., Guillette, L.J., Palanza, P., Parmigiani, S., Swan, S.H. and vom Saal, F.S. The emerging science of endocrine disruption. R. C. Ragaini, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 30th Session, Erice, Sicily, August, 2003, World Scientific Publishers, Singapore, pp. 105-121, 2004.

vom Saal, F.S., Richter, C.A., Ruhlen, R.R. Nagel, S.C. and Welshons, W.V. Disruption of laboratory experiments due to leaching of bisphenol a from polycarbonate cages and bottles and uncontrolled variability in components of animal feed. Proceedings from the International Workshop on Development of Science-Based Guidelines for Laboratory Animal Care, National Academies Press, Washington DC, 65-69, 2004.

2003

Nagel, S.C. and vom Saal, F.S. Endocrine control of sexual differentiation: Effects of the
maternal-fetal environment and endocrine disrupting chemicals
. In: Principles of Sex-Based Physiology, Ed. V. Miller and M. Hay. Elsevier, pp. 15-37, 2003.

Howdeshell, KL Peterman, P.H., Judy, B.M., Taylor, J.A., Orazio, C.E., Ruhlen, R.L., vom Saal, F.S. and Welshons, W.V. Bisphenol a is released from used polycarbonate animal cages into water at room temperature. Environ. Health Perspect, 111:1180-1187, 2003.

Rice, C., Birnbaum, L.S., Cogliano, J., Mahaffey, K., Needham, L., Rogan, W. and. vom Saal, F.S. Exposure assessment for endocrine disruptors: some considerations in the design of studies. Environ. Health Perspect., 111:1683-1690, 2003.

Parmigiani, S., Palanza, P., Colborn, T. and vom Saal, F.S. Exposure to very low doses of endocrine disrupting chemicals (EDCs) during fetal life permanently alters brain development and behavior in animals and humans. R. C. Ragaini, Editor, Proceedings of Conference: International Seminar on Nuclear War and Planetary Emergencies, 27th Session, Erice, Sicily, August, 2002, World Scientific Publishers, Singapore, pp. 293-308, 2003.

Welshons, W.V., Thayer, K.S., Taylor, J., Judy, B. and vom Saal, F.S. Large effects from
small exposures: I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity
. Environ. Health Perspect, 111: 994-1006, 2003.

2002

Alworth, L., Howdeshell, K.L., Ruhlen, R. And vom Saal, F.S. Uterine responsiveness to
estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and
methoxychlor in CD-1 mice: Effects of low versus high doses
. Toxicology and Applied
Pharmacology 183:10-22, 2002.

Palanza, P., Howdeshell, K.L., Parmigiani, S. and vom Saal, F.S. Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environ. Health Perspect. 110:415-422, 2002.

Timms, B.G., Peterson, R.E. and vom Saal, F.S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin
interacts with endogenous estradiol to disrupt prostate gland morphogenesis in male rat
fetuses
. Toxicological Sciences 67:264-274, 2002.

Ottinger, M.A. and vom Saal, F.S. Impact of Environmental Endocrine Disruptors on Sexual Differentiation in Birds and Mammals. In: Hormones, Brain and Behavior, Ed. D. Pfaff, Academic Press, New York, pp 325-383, 2002.

Palanza, P. Morellini, F., Paarmigiani, S. and vom Saal, F. Ethological methods to study the effects of maternal exposure to estrogenic endocrine disrupters: A study with methoxychlor. Neurotoxicology and Teratology 24:55-69, 2002.

2001

Palanza, P., Parmigiani, S. and vom Saal, F.S. Effects of prenatal exposure to low doses of
diethylstilbestrol, o,p’DDT and methoxychlor on postnatal growth and neurobehavioral
development in male and female mice
. Horm. Behav. 252-265, 2001.

Thayer, K.A., R. Ruhlen, R., Howdeshell, K.L., Buchanan, D., Cooke, P.S., Welshons, W.V., Haseman, J. and vom Saal, F.S. Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17α- ethinyl estradiol. Human Reproduction 16:988-996, 2001.

2000

vom Saal, F.S. and Welshons, W.V. NIH panel confirms that endocrine disrupting chemicals cause effects at very low doses. Risk Policy Report 7(11):47-50, November 30, 2000. Inside Washington Publishers. Source: Risk Policy Report via InsideEPA.com

Wang, M-S. and vom Saal, F.S. Maternal age influences traits in offspring. Nature, 407:469-470, 2000.

Howdeshell, K.L. and vom Saal, F.S. Developmental exposure to bisphenol A: Interaction
with endogenous estradiol during pregnancy in mice
. American Zoologist 40: 429-437, 2000.

1999

Howdeshell, K.L., Hotchkiss, A.K., Thayer, K.A., Vandenbergh, J.G. and vom Saal, F.S.
Exposure to bisphenol A advances puberty. Nature 401:763-764, 1999.

Palanza, P. Morellini, F., Parmigiani, S. and vom Saal, F.S. Prenatal exposure to endocrine
disrupting chemicals: Effects on behavioral development
. Neurosci. Biobeh. Rev. 23:1011-1027, 1999.

Bigsby, R. Chapin, R., Daston,G., Davis, B., Gorski, J., Gray, E., Howdeshell, K. Zoeller, T. and vom Saal, F. Evaluating the effects of endocrine disruptors on endocrine function during development. Environ. Health Perspect. 107 (Suppl 4):613-618, 1999.

Welshons, W.V., Nagel, S.C., Kristina A. Thayer, K.A., Judy, B.M. and vom Saal, F.S.
Development of in vitro assays to predict activity of xenoestrogens in animals: fetal exposure to methoxychlor and other xenoestrogens increases adult prostate size in mice. Tox. Ind.Health, 15:12-25, 1999.

vom Saal, F.S., Clark, M.M., Galef, B.G., Drickamer, L.C. and Vandenbergh, J.G. The
intrauterine position (IUP) phenomenon
. In: Encyclopedia of Reproduction. Eds E. Knobil and J. Neill. Academic Press, New York, Volume 2, pp. 893-900, 1999.

Timms, B.G., Petersen, S.L. and vom Saal, F.S. Prostate gland growth during development is stimulated in both male and female rat fetuses by intrauterine proximity to female fetuses. J. Urol.161:1694-1701, 1999.

vom Saal, F.S. and Timms, B.G. The role of natural and manmade estrogens in prostate development. In: R.K. Naz, ed. Endocrine Disruptors: Effects on Male and Female Reproductive Systems. CRC Press, Boca Raton, FL, 307-327, 1999.

Nagel, S.C., vom Saal, F.S. And Welshons, W.W. Developmental effects of estrogenic chemicals are predicted by an in vitro assay incorporating modification of cell uptake by serum. J. Steroid Biochem. Mol. Biol. 69:343-357, 1999.

Palanza, P., Parmigiani, S., Huifen Liu, H. and vom Saal, F.S. Prenatal exposure to low
doses of the estrogenic chemicals diethylstilbestrol and o,p’-DDT alters aggressive behavior of male and female house mice
. Pharmacology Biochemistry and Behavior 64:665-672, 1999.

1998

vom Saal, F.S., Cooke, P.S., Palanza, P., Thayer, K.A., Nagel, S., Parmigiani, S. and
Welshons, W.V. A physiologically based approach to the study of bisphenol A and other
estrogenic chemicals on the size of reproductive organs, daily sperm production and
behavior
. Toxicol. Industrial Health, 14:239-260, 1998.

Welshons, W.W., Nagel, S.C., and vom Saal, F.S. Response to The Importance of Protocol Design and Data Reporting to Research on Endocrine Disruption. Environ. Health Perspect. 106: 316-317, 1998.

Nagel, S.C., vom Saal, F.S. And Welshons, W.V. The effective free fraction of estradiol and xenoestrogens in human serum measured by whole cell uptake assays: Physiology of
delivery modifies estrogenic activity
. Proc. Soc. Exp. Biol. Med. 217:300-309, 1998.

vom Saal, F.S. and Sheehan, D.M. Challenging risk assessment. Forum for Appllied
Research and Public Policy, 13(3):11-18, 1998.

Parmigiani, S., Palanza, P. and vom Saal, F.S. Ethotoxicology: An evolutionary approach to the study of environmental endocrine disrupting chemicals. J. Toxicol. Industrial Health
14:333-340, 1998.

1997

Nagel, S.C., vom Saal, F.S., Thayer, K.A., Dhar, M.G., Boechler, M. and Welshons, W.V.
Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. Environ. Health Perspect. 105:70-76, 1997.

vom Saal, F.S., Timms, B.G., Montano, M.M., Palanza, P. Thayer, K.A., Nagel, S.C., Dhar, M.D., Ganjam, V.K., Parmigiani, S. and Welshons, W.V. Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses. Proc. Nat. Acad. Sci., 94:2056-2061, 1997.

Welshons, W.V., vom Saal, F.S. and Nagel, S.C. Bisphenol A in food cans: An Update.
Environ. Health Perspect.105:571-572, 1997.

Sheehan, D.M. and vom Saal, F.S. Low dose effects of hormones: A challenge for risk
assessment.
 Risk Policy Report 4(9) 31-39, 1997.

vom Saal, F.S. Getting to the truth: What we know and don’t know about the hazards of
endocrine disrupting chemicals
. Pesticides and You 17:9-16, 1997.

1996

Walker, S.E., Keisler, L.W., Caldwell, C.W., Kier, A.B. and vom Saal, F.S. Effects of altered prenatal hormonal environment on expression of autoimmune disease in NZB/NZW mice. Environ. Health Perspect. 104:815-821, 1996.

vom Saal, F.S. Spirituality and Sustainability: Man-Made Chemicals and Health of the Unborn. 1996.

1995

Palanza, P., Parmigiani, S. and vom Saal, F.S. Correlation between anogenital distance at
birth, maternal aggression and stimulus characteristics of wild female mice
. Physiol. Behav. 58: 827-835, 1995.

vom Saal, F.S. Environmental estrogenic chemicals: Their impact on embryonic
development
. Human Ecol. Risk Assess (HERA) 1(2):3-15, 1995.

vom Saal, F.S., Franks, P., Boechler, M., Palanza, P. and Parmigiani, S. Nest defense in
highly aggressive wild canadian house mice: Effect of presence of the stud male
. Physiol.
Behav., 58:669-678, 1995.

Keisler, L.W., vom Saal, F.S., Keisler, D.H., Rudeen, P.K. and Walker, S.E. Aberrant
hormone balance in fetal autoimmune NZB/W mice following prenatal exposure to
testosterone excess or the androgen blocker flutamide
. Biol. Reprod. 53:1190-1197, 1995.

Montano, M.M., Welshons, W.V. and vom Saal, F.S. Free estradiol in serum and brain uptake of estradiol during fetal and neonatal sexual differentiation in female rats. Biol. Reprod., 53:1198-1207, 1995.

Drickamer, L.C., vom Saal, F.S., Marriner, L.M. and Clover, C. Anogenital distance and
aggression in male house mice (Mus domesticus)
. Aggressive Behav., 21:301-309, 1995.

vom Saal, F.S., Nagel, S.C., Palanza, P., Boechler, M., Parmigiani, S. Welshons, W.
Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure
during fetal life on subsequent territorial behavior in male mice
. Tox. Let. 77:343-350, 1995.

1994

vom Saal, F.S. Genetic, Hormonal and Environmental Factors that Influence Reproductive Traits in Mice. 1994

Even, M.D, Laughlin, M.H., Krause, G.F. and vom Saal, F.S. Blood flow to uterine segments and placentae differs as a function of uterine location, side, and fetal sex in pregnant rats. J. Reprod. Fertil., 102:245-252, 1994.

vom Saal, F. The role of social, religious and medical practices in the neglect, abuse,
abandonment and killing of infants
. In: Infanticide and Parental Care. S. Parmigiani and F.
vom Saal (Eds). Harwood Academic Press, London, 43-72, 1994.

Palanza, P., Parmigiani, S. and vom Saal, F.S. Maternal aggression toward infanticidal males of different social status in wild house mice. Aggressive Behavior 20:267-274, 1994.

vom Saal, F.S., Finch, C.E. and Nelson, J.F. Natural history and mechanisms of aging in
humans, laboratory rodents and other selected vertebrates
. In: Physiology of Reproduction, E. Knobil, J. Neill and D. Pfaff (Eds.), Raven Press, New York, 2nd edition, Vol 2, pp 1213-1314, 1994.

Palanza, P., Parmigiani, S. and vom Saal, F.S. Male urinary cues stimulate intrasexual
aggression and urine marking in wild female mice
. Animal Behaviour 48:245-247, 1994.

1993

Perrigo, G., Belvin, E. and vom Saal, F. Social inhibition of infanticide in male house mice. Ecol. Ethol. Evol. 5:181-185, 1993.

Perrigo, G. and vom Saal, F. Behavioral Cycles and the Neural Timing of Infanticide and Parental Behavior in Male House Mice. 1993

Colborn, T., vom Saal, F.S. and Soto, A.M. Developmental effects of endocrine disrupting
chemicals in wildlife and humans
. Environ. Health Perspectives 101:378-384,1993.

Montano, M., Wang, M. vom Saal, F. Sex difference in serum concentrations of
corticosterone in mouse fetuses is mediated by differential placental transport from the
mother and eliminated by maternal adrenalectomy of stress
. J. Reprod. Fertil. 99: 283-290, 1993.

1992

Nonneman, D.J., Ganjam, V.K., Welshons, W.V., vom Saal, F.S. Intrauterine position effects on steroid metabolism and steroid receptors of reproductive organs in male mice. Biol. Reprod. 47:723-729, 1992.

Perrigo, G., Belvin, E. and vom Saal, F. Time and sex in the male mouse: Temporal
regulation of infanticide and parental behavior
. Chronobiol. Int., 9:421-433, 1992.

Clark, M.M., vom Saal, F.S. and Galef, B.G. Intrauterine positions and testosterone levels of adult male gerbils are correlated. Physiol. Behav. 51:957-960, 1992.

vom Saal, F.S. and Dhar, M. D. Blood flow in the uterine loop artery and loop vein is bi-driectional in the mouse: Implications for intrauterine transport of steroids. Physiol. Behav., 52: 163-171, 1992.

Even, M.D., Dhar, M. and vom Saal, F.S. Transport of steroids between fetuses via amniotic fluid in relation to the intrauterine position phenomenon in rats. J. Reprod. Fertil. 96:709-716, 1992.

1991

Even, M. and vom Saal, F. Seminal vesicle and preputial gland response to steroids in adult male mice is influenced by prior intrauterine position. Physiol. Behav., 51:11-16, 1991.

Montano, M., Wang, M., Even, M. and vom Saal, F. Serum corticosterone in fetal mice: Sex differences, circadian changes, and effect of maternal stress. Physiol. Behav. 50: 323-329, 1991.

Keisler, L., vom Saal, F., Keisler, D. and Walker, S. Hormonal manipulation of the prenatal environment alters reproductive morphology and increases longevity in autoimmune NZB/Wmice. Biol. Reprod. 44: 707-716, 1991.

vom Saal, F., Even, M. and D. Quadagno, D. Effects of maternal stress on puberty, fertility and aggressive behavior of female mice. Physiol. Behav., 49: 1073-1078, 1991.

Perrigo, G., Belvin, E. and vom Saal, F. Individual variation in neural timing of infanticide and parental behaviour in male mice. Physiol. Behav. 50: 287-296, 1991.

1990

Rohde-Parfet, K., Lamberson, W. Rieke, A., Cantley, T. Ganjam, V., vom Saal, F. and Day, B. Intrauterine position effects in male and female swine: subsequent survivability, growth rate, morphology and semen characteristics. J. Anim. Sci., 68:179-185, 1990.

Perrigo, G., Bryant, W. and vom Saal, F. A unique neural timing system prevents male mice from harming their own offspring. Anim. Behav., 39:535-539, 1990.

vom Saal, F., Quadagno, D., Even, M., Keisler, L., Keisler, D., and Khan, S. Paradoxical
effects of maternal stress on fetal steroids and postnatal reproductive traits in female mice
from different intrauterine positions
. Biol. Reprod., 43:751-761, 1990.

vom Saal, F.S. Prenatal gonadal influences on mouse sociosexual behaviours. In M. Haug,
P.F. Brain, and C. Aron, (Eds.). Heterotypical Behaviour in Man and Animals. Chapman and Hall, London, pp. 42-70, 1990.

Perrigo, G., Belvin, L. and vom Saal, F. Humane behavioral assays in the laboratory: An
alternative test for assessing how rodents behave toward young
. Humane Innovations and
Alternatives in Animal Experimentation: 4: 208-209, 1990.

1989

vom Saal, F.S. Sexual differentiation in litter-bearing mammals: influence of sex of adjacent fetuses in utero. J. Anim sci. 67:1824-1840, 1989.

vom Saal, F.S. The production of and sensitivity to cues that delay puberty and prolong subsequent oestrous cycles in female mice are influenced by prior intrauterine position. J. Reprod. Fert. 86:457-471, 1989.

Perrigo, G. and vom Saal, F. Mating-induced regulation of infanticide in male mice: Fetal programming of a unique stimulus-response. In: Ethoexperimental Approaches to the Study of Behavior. Edited by R. Blanchard, P. Brain, D. Blanchard and S. Parmigiani. Kluwer Academic Pub., Dordrecht, The Netherlands, pp. 320-333, 1989.

Perrigo, G., Bryant, W. and vom Saal, F. The use of live pups in a humane, injury-free test for infanticidal behaviour in male mice. Anim. Behav. 38:897-904, 1989.

Perrigo, G., Bryant, W. and vom Saal, F. Fetal, hormonal and experiential factors influencing the mating-induced regulation of infanticide in male house mice. Physiol. Behav. 46: 121-128, 1989.

1988

vom Saal, F. and Finch, C. Reproductive senescence: Phenomena and mechanisms in mammals and selected vertebrates. In: Physiology of Reproduction, E. Knobil, J. Neill and D. Pfaff (Eds.), Raven Press, New York, pp. 2351-2413, 1988.

vom Saal, F. Perinatal testosterone exposure has opposite effects on intermale aggression and infanticide in mice. In: House Mouse Aggression. Edited by P. Brain and S. Parmigiani. Gordon and Breach Science Pub., pp. 179-204, 1988.

1986

McCarthy, M. and vom Saal, F. Inhibition of infanticide after mating in wild male house mice. Physiol. Behav. 36:203-209, 1986.

McCarthy, M., Bare, J. and vom Saal, F. Infanticide and parental behavior in wild female house mice (Mus musculus): Effects of ovariectomy, adrenalectomy, and administration of oxytocin and prostaglandin. Physiol. Behav. 36:17-23, 1986.

McCarthy, M. and vom Saal, F. Infanticide by virgin CF-1 and wild male house mice (Mus musculus): Effects of age, prolonged isolation and testing procedure. Develop. Psychobiol. 19:279-290, 1986.

1985

vom Saal, F. Time-contingent change in infanticide and parental behavior induced by ejaculation in male mice. Physiol. Behav. 34:7-15, 1985.

vom Saal, F. and Moyer, C. Prenatal effects on reproductive capacity during aging in female mice. Biol. Reprod. 32:1116-1126, 1985.

McCarthy, M. and vom Saal, F. The influence of reproductive state on infanticide by wild female house mice. Physiol. Behav. 35:843-849, 1985.

1984

vom Saal, F. Proximate and ultimate causes of infanticide in male house mice. In: Infanticide: Comparative and Evolutionary Aspects, G. Hausfater and S. Blaffer-Hrdy (Eds.), Aldine Pub., 1984, pp. 401-424.

vom Saal, F. The intrauterine position phenomenon: Effects on physiology, aggressive behavior and population dynamics in house mice. In: Prog. Clin. Biol. Res., Vol. 169, Biological Perspectives on Aggression, K. Flannelly, R. Blanchard and D. Blanchard (Eds.), Liss, New York, pp. 135-179, 1984.

Rines, J. and vom Saal, F. Fetal effects on sexual behavior and aggression in young and old female mice treated with estrogen and progesterone. Horm. Behav. 18:117-129, 1984.

1983

vom Saal, F., Grant, W., McMullen, C. and Laves, K. High fetal estrogen titers correlate with enhanced adult sexual performance and decreased aggression in male mice. Science
220:1306-1309, 1983.

vom Saal, F. Variation in infanticide and parental behavior in male mice due to prior intrauterine proximity to female fetuses: Elimination by prenatal stress. Physiol. Behavior. 30:675-681, 1983.

vom Saal, F. Models of early hormonal effects on intrasex aggression in mice. In: Hormones and Aggressive Behavior, B. Svare (Ed.), Plenum, New York, pp. 197-222, 1983.

vom Saal, F. The interaction of circulating estrogens and androgens in regulating mammalian sexual differentiation. In: Hormones and Behavior in Higher Vertebrates, J. Balthazart, E. Prove and R. Giles (Eds.), Springer Verlag, Berlin, pp. 159-177, 1983.

1982

vom Saal, F. Intrauterine positioning of male and female fetuses influences prenatal hormone titers and adult behavior. In: Proceedings of the Fifth World Congress of Sexology, Exerpta Medica, Amsterdam, 1982.

vom Saal, F. and Howard L. The regulation of infanticide and parental behavior: Implications for reproductive success in male mice. Science 215:1270-1272, 1982.

1981

vom Saal, F., Pryor, S. and Bronson, F. Effects of prior intrauterine position and housing on oestrous cycle length in adolescent mice. J. Reprod. Fert. 62:33-37, 1981.

vom Saal, F. Variation in phenotype due to random intrauterine positioning of male and female fetuses in rodents. J. Reprod. Fert. 62: 633-650, 1981.

vom Saal, F. The intrauterine position phenomenon in mice. In: Biology of Aggression, P. Brain and D. Benton (Eds.), Sijthoff and Noordhoff, Netherlands, pp. 231-236, 1981.

1980

vom Saal, F. and Bronson, F. Sexual characteristics of adult female mice are correlated with their blood testosterone levels during prenatal development. Science 208:597-599, 1980.

vom Saal, F. and Bronson, F. Variation in length of the estrous cycle in mice due to former intrauterine proximity to male fetuses. Biol. Reprod. 22:777-780, 1980.

1979

Bronson, F. and vom Saal, F. The preovulatory surge in luteinizing hormone secretion in mice: Variation in magnitude due to ambient light intensity. Biol. Reprod. 20:1005-1008, 1979.

Bronson, F. and vom Saal, F. Control of the release of luteinizing hormone by steroids in the mouse. Endocrinol. 104:1247-1255, 1979.

vom Saal, F. Prenatal exposure to androgen influences morphology and aggressive behavior of male and female mice. Horm. Behav. 12: 1-11, 1979.

1978

vom Saal, F., Timmons, R. and Hamilton, L. Effects of diet and dietary experience on body weight regulation in rats with septal lesions. Physiol. Psychol. 6:306-313, 1978.

vom Saal, F. and Bronson, F. In utero proximity of female mouse fetuses to males: Effect on reproductive performance during later life. Biol. Reprod. 19:842-853, 1978.

vom Saal, F. Cyproterone acetate exposure during gestation in mice retards fetal growth. Physiol. Behav. 21:515-517, 1978.

1977

Gandelman, R. and vom Saal, F. Exposure to early androgen attenuates androgen-induced pup-killing in male and female mice. Behav. Biol. 20:252-260, 1977.

1976

vom Saal, F., Svare, B. and Gandelman, R. Time of neonatal androgen exposure influences length of testosterone treatment required to induce aggression in adult male and female mice. Behav. Biol. 17:391-397, 1976.

vom Saal, F., Gandelman, R. and Svare, B. Aggression in male and female mice: Evidence for changed neural sensitivity in response to neonatal but not adult androgen exposure. Physiol. Behav. 17:53-57, 1976.

1975

vom Saal, F., Hamilton, L. and Gandelman, R. Faster acquisition of an olfactory discrimination following septal lesions in male albino rats. Physiol. Behav. 14:697-703, 1975.

Gandelman, R. and vom Saal, F. Pup-killing in mice: The effects of gonadectomy and testosterone administration. Physiol. Behav. 15:647-651, 1975.